Transit Bipartition

30.3%

oranında insan ülkemizde obezite hastalığı ile yaşamaktadır.

49%

oranıyla kötü beslenme obezitenin en önemli nedenidir.

6000+

başarıyla tamamlanmış cerrahi operasyon deneyimi

TRANSIT BIPARTITION

What is Transit Bipartition?

Transit Bipartition is one of the surgical options that can be planned in the treatment of Type 2 Diabetes. Technically, it is an operation that both restricts food intake and reduces the absorption of food. Unlike other gastric bypass surgeries, food continues to pass through all the existing small intestine tissue, there is no bypassed small intestine segment, and it does not cause serious malabsorption of food and vitamins. The surgery is performed laparoscopically.

Transit Bipartition surgery is only applied to patients with Type 2 diabetes, but it can also be safely applied to obese patients who aim to reduce insulin resistance with weight loss. Transit bipartition is the safest and most effective method of surgery for patients who do not prefer or are not eligible for sleeve gastrectomy (tube stomach) or gastric bypass surgery. Transit Bipartition is the type of surgery that should be preferred instead of Gastric Bypass surgeries (such as Roux-en-Y or Mini Gastric Bypass) because gastric bypass surgeries are in a relatively high-risk surgical group in terms of postoperative complications.

TRANSIT BIPARTITION

How is Transit Bipartition Surgery Performed?

The surgery is performed laparoscopically. The surgery starts with a sleeve gastrectomy (limiting the stomach volume to 40-50%), then the last parts of the small intestine are measured and marked, and a segment of the intestine which is approximately 3 meters long is directed upwards through a second hole to the stomach. Thus, the food coming into the stomach proceeds in both the normal anatomical way (follows the gastric outlet 66% of the time) and through the newly made route (33% of the time). As a result, food intake is reduced by partially shrinking the stomach, 2/3 of the food taken proceeds in the usual way, and 1/3 reaches the last part of the small intestine (ileum) faster from the second exit. Progression of the food taken in the normal passage prevents any malabsorption and vitamin/mineral deficiencies to develop. The easier and fast access of food to the last part of the small intestine, on the other hand, ensures existing insulin to work more effectively. Insulin enters the circulation earlier and balances the blood glucose level. This stimulation results in the improvement of the disease by increasing the rate and efficiency of insulin secretion from the pancreas.

The operation is completed in 60-120 minutes. The most important factor determining the duration is the person’s weight, anatomy and previous surgeries, if any.

TRANSIT BIPARTITION

What are the advantages of Transit Bipartition Surgery?

The reduction of the stomach size and volume, allows the feeling of satiety to occur earlier with less food consumption. A balanced diet, calorie restriction, and less food intake would allow the patient to lose weight controllable.

The fundus (upper region) part of the stomach produces a hormone called ghrelin, which is stimulated in cases of hunger and alerts the brain to eat. The removal of the fundus reduces ghrelin production, which facilitates and expedites weight loss further.

The food coming into the stomach proceeds in both the normal anatomical way (follows the gastric outlet 66% of the time) and through the newly made route (33% of the time). As a result, food intake is reduced by partially shrinking the stomach, 2/3 of the food taken proceeds in the usual way, and 1/3 reaches the last part of the small intestine (ileum) faster from the second exit. Progression of the food taken in the normal passage prevents any malabsorption and vitamin/mineral deficiencies to develop.

Although the flow direction and integrity of the small intestines are changed, there is no small intestine area that does not pass food. Half of the ingested food proceeds through its normal route and undergoes the digestive process, while the remaining half is digested less and absorbed less.

Transit Bipartition is the type of surgery that should be preferred instead of Gastric Bypass surgeries (such as Roux-en-Y or Mini Gastric Bypass) because gastric bypass surgeries are in a relatively high-risk surgical group in terms of postoperative complications.

Transit Bipartition surgery can be reverted to Sleeve gastrectomy surgery, the intestines can be easily reverted to their former order. At the same time, in case of development of diabetes, further conversion to Diverted ileal Interposition surgery can be performed. It is possible to transform into surgeries that also disrupt absorption (from transit bipartition surgery back to sleeve gastrectomy / forward conversion to derivative surgeries such as Diverted Ileal Interposition).

Its weight loss effectiveness is long, and the rate of reaching the targeted weight and maintaining the achieved weight is at the level of 80-90%.

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Surgery Process

The routine approach is to evaluate the patients in the preoperative period and to take possible precautions by determining the risks. All patients should be examined in detail during the process of planning the surgery. The main purpose is to detect and treat possible deficiencies and diseases before the operation, and, if necessary, postpone the surgery.

The assessments that have to be done for this purpose, are; evaluation of the lung (such as chest X-ray, pulmonary function tests, consultation from a pulmonologist), assessment of the heart (ECG, ECHO, cardiology consultation, and further examinations like stress ECG, Holter, or angiography if necessary), psychiatric evaluations (questioning the history of drug use, substance abuse, presence of psychiatric disease, and psychiatric consultation), surgical tests (abdominopelvic ultrasonography, doppler ultrasonography, history of previous abdominal surgeries), internal medicine (non-surgical) evaluations (existence of other diseases and treatments being used, internal medicine consultation, etc.), endoscopic exploration (visual assessment of the esophagus, stomach, and small intestine with endoscopy), laboratory tests (blood work, assessment of liver functions, kidney functions, and establishing the bleeding time).

The medications used by the patients should also be taken into account (such as blood thinners, antihypertensive and antidiabetic drugs, and psychiatric drugs). During the operation, some drugs should be discontinued or replaced with other medications, and re-continued after the surgery, as soon as possible.

In the presence of additional comorbidities (like previous operations, heart attack, lung infections, neurological and psychiatric diseases, hypertension, diabetes, and obstructive sleep apnea syndrome), the patient should be checked in the relevant department, and the evaluations and suggestions of the specialist there should be taken into account.

The medications used by the patient must be evaluated, and their use, dosage, or discontinuation in pre-and post-operative time should be planned.

High-risk patients must be hospitalized and treated before the operation.

Patients who have undergone surgery are evaluated by the anesthesia team and if allowed, taken up their rooms for further follow-up after waking up. There is no need for the patient to be followed in the intensive care unit after the surg ery (except for special cases such as sleep-apnea). 6 hours after the operation, the patient can start to drink water in a controlled manner, while the patient stands up and takes mini walks. One day after the operation, the patient’s walking frequency is increased and the patient is supported with breathing exercises. Consumption of liquid foods (such as seedless soup, compote) is started in a controlled manner following the gas discharge. The drain is removed during this process. In order to observe the clinical situation and to catch possible complications, the patient stays in the hospital for a total of 3 nights and is discharged on the 4th day.

Before discharge, all details of nutrition are explained to the patient and their relatives, under the control of a dietitian, and the drugs that the patient will use and the points to be considered are explained in detail.

Postoperative diet and nutrition are explained under the control of a dietitian. Questions such as what should be eaten in the early process, at what speed and interval should it be consumed, what should not be eaten are answered.

Patients are given a 1-month diet program to follow. The main purpose here is not to weaken the patient quickly, but to ensure the safe healing of the surgical field and not to endanger the safety of the suture line with excessive-incorrect consumption.

From the first month, nutrition returns to normal in terms of consistency. In order to ensure a healthy life and controlled weight loss, foods that should not be consumed are explained in detail and the patient’s adaptation process and weight loss are monitored monthly.

The drugs that should be used in the first month after the surgery are stomach protectors, multivitamins and pain relievers if needed. These drugs are released in a controlled manner after the first month.

The drugs used in the pre-operative period are started again. In the case of regression of some weakening-related diseases (such as hypertension, hypercholesterolemia), the drugs used are left in a controlled manner in line with the knowledge and recommendation of the relevant physician.

Although every surgical intervention has some complications and risks, there are complications and risks specific to each surgery. What scientifically important is the occurrence and treatability of these complications.

Complications that can be seen in laparoscopic metabolic surgery are; bleeding through surgical incisions, wound problems (such as surgical site infections, and poor wound healing), specific complications (like surgical site bleeding, and leaks after the disruption of the site’s integrity), positional complications of the structural integrity of the stomach (strictures throughout the passage, twisting of the stomach around itself (torsion), etc.), post-surgical complications unrelated to the surgical site (such as lung infections, urinary tract infections, heart problems), long-term complications (weight loss faster or slower than expected, ineffective/inactive weight loss or weight gain, vitamin and mineral deficiencies).

The incidence of these complications ranges from one percent to 1 in 10 thousand to even 1 in 100 thousand. At this point, what’s important is the early diagnosis of preventable complications and the application of appropriate treatment when they occur. Likewise, identification of the causes that increase the risk of complications even before the surgery (such as the presence of other diseases, smoking, alcohol, other factors affecting wound healing, or other diseases that may increase the adverse side effects of anesthesia) and if necessary removing these risk factors first, reduces the prevalence of the complications considerably. Similarly, precautions for postoperative complications can be taken (such as early mobilization, respiratory muscle training, strict aftercare and follow-up, and early initiation of appropriate medical treatment) to ensure the process is completed without any problems.

Another important point in the postoperative period is the early detection and appropriate treatment of undesirable complications. The fact that “Early diagnosis saves lives”, which is always said in diseases such as cancer, is valid for every aspect of medicine, especially in surgical complications. Unfortunately, failure to diagnose a complication at an early stage that can be brought under control with appropriate treatment can cause the situation to worsen and may become uncontrollable and untreatable. Therefore, it is important to inform and check in with the patients at every step and to follow up with the patient closely after the surgery. It should never be forgotten that the experience and knowledge of the surgical team is the most important component in the management of surgical complications.

Frequently Asked Questions

Initially, the first requirement is to have Type 2 diabetes, and additionally to have an appropriate pancreatic reserve capacity in terms of insulin secretion. At the same time, with adequate insulin reserve, adequate release response of insulin in satiety is the feature sought. In patients with adequate insulin production and secretion, the use of oral antidiabetic pills (OAD) and/or insulin does not constitute a contraindication to surgery. The presence of additional diseases (obesity, hypertension, asthma, sleep-apnea syndrome) is not an obstacle to surgery; on the contrary, symptoms may regress after surgical intervention. Although previous abdominal surgeries make the operation difficult, it is not an obstacle for the operation to be performed in the same way. The use of sugar pills and insulin ends in the early postoperative period, the use of antihypertensive and anticholesterol drugs is terminated in the later period, and the use of sleep apnea devices such as CPAP is stopped in a controlled manner. Patients eligible for surgery should also undergo internal, cardiological, and anesthetic consultations.
In sleeve gastrectomy surgeries, the cutting of the stomach is done with a stapling system called as laparoscopic linear cutter staplers. Even if the staple line is safely closed after the procedure, bleeding may occur along the line. Scientific studies in recent years show that suturing the staple line significantly reduces the risk of bleeding in the early postoperative period. Similarly, it is known that suturing the line reduces the leakage rate. Therefore, we strongly recommend suturing the staple line in order to reduce the risk of surgical complications.
Post-operative walks are started as soon as possible. After the second week, sports such as brisk walking and swimming can be done. After the first month, weightless exercises can be started (such as pilates). As of the third month, weighted sports can be done easily (such as fitness, weighted exercises).
If the wound sites are closed subcutaneously (aesthetically) after the surgery, there is no need to remove the sutures. In patients whose stitches have to be closed normally, the stitches are removed after 12-15 days.
The period with the highest weight loss after surgery is the first month. The reasons for this are a low-calorie diet with liquid foods and the loss of excess fluid in the body, along with normal fat loss. After the balance is achieved, weight loss is parallel to the lost fat. The average weight loss seen in the first month is 5-15 kilograms.
Some patients may experience skin sagging after weight loss surgeries. What determines this is related to how overweight the person is, the presence of sagging before the surgery, and the rate of weight loss. It is recommended that surgeries related to sagging be postponed until after weight loss is complete.
After the post-operative staple line is healed, the stomach may stretch a little, but the stomach does not enlarge.
The weight loss status of the patients after the surgery is followed up on a monthly basis by contacting them. Blood evaluations are made in the 1st, 3rd, 6th, 9th and 12th months.

Because there is not enough insulin in type 1 diabetic patients, these patients cannot benefit from surgery, so these patients should not have surgery and should continue to use insulin. In type 2 diabetes patients, patients with inadequate pancreatic reserve are not operated on.

Surgery is contraindicated to patients with severe heart failure, uncontrolled cardiovascular disease, end-stage lung disease, cancer or treated for cancer, cirrhosis in the presence of portal hypertension, uncontrolled substance or alcohol abuse, and people with severely impaired intellectual capacity.